2-thiophenecarbonyl chloride, 3-bromo-
3-Bromothiophene-2-carbonyl chloride
CAS: 25796-68-3
Molecular Formula: C5H2BrClOS
2-thiophenecarbonyl chloride, 3-bromo- - Names and Identifiers
2-thiophenecarbonyl chloride, 3-bromo- - Physico-chemical Properties
| Molecular Formula | C5H2BrClOS |
| Molar Mass | 225.49 |
| Density | 1.855±0.06 g/cm3(Predicted) |
| Melting Point | 65-68°C |
| Boling Point | 135-136°C 13mm |
| Flash Point | 109.4°C |
| Vapor Presure | 0.0147mmHg at 25°C |
| Refractive Index | 1.618 |
2-thiophenecarbonyl chloride, 3-bromo- - Risk and Safety
| Risk Codes | 34 - Causes burns |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | 3261 |
2-thiophenecarbonyl chloride, 3-bromo- - Introduction
chloride is an organic compound with the chemical formula C6H3BrClOS. The following is a description of some of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: colorless or light yellow liquid
-Melting point:-5 ℃
-Boiling point: 120-121 ℃
-Density: 1.721g/cm³
-High volatility at room temperature
-Reacts slowly with water and can be decomposed into toxic gases
Use:
-chloride can be used as an important intermediate in drug synthesis and Organic synthesis
-It can be used to synthesize biologically active compounds, such as drugs, pesticides, etc.
-Can also be used as a chlorinating agent or acylating agent in organic synthesis reactions
Method:
-chloride can be prepared by reacting 3-bromothiophene-2-carboxylic acid with thionyl chloride (SOCl2)
-Under the reaction conditions, mix 3-bromothiophene-2-formic acid and thionyl chloride in a molar ratio of 1:2, heat and react to generate chloride
Safety Information:
-chloride is an organic halogen compound, which has certain toxicity and irritation
-Need to pay attention to protective measures when using, such as wearing protective glasses, gloves and protective clothing
-Avoid contact with skin, eyes and respiratory tract
-Operate in a well-ventilated place to avoid inhaling harmful gases
-Ensure that it is well sealed during storage, away from fire and high temperature, and avoid exposure to sunlight
-Comply with relevant safety operation instructions and regulations when using or disposing
Nature:
-Appearance: colorless or light yellow liquid
-Melting point:-5 ℃
-Boiling point: 120-121 ℃
-Density: 1.721g/cm³
-High volatility at room temperature
-Reacts slowly with water and can be decomposed into toxic gases
Use:
-chloride can be used as an important intermediate in drug synthesis and Organic synthesis
-It can be used to synthesize biologically active compounds, such as drugs, pesticides, etc.
-Can also be used as a chlorinating agent or acylating agent in organic synthesis reactions
Method:
-chloride can be prepared by reacting 3-bromothiophene-2-carboxylic acid with thionyl chloride (SOCl2)
-Under the reaction conditions, mix 3-bromothiophene-2-formic acid and thionyl chloride in a molar ratio of 1:2, heat and react to generate chloride
Safety Information:
-chloride is an organic halogen compound, which has certain toxicity and irritation
-Need to pay attention to protective measures when using, such as wearing protective glasses, gloves and protective clothing
-Avoid contact with skin, eyes and respiratory tract
-Operate in a well-ventilated place to avoid inhaling harmful gases
-Ensure that it is well sealed during storage, away from fire and high temperature, and avoid exposure to sunlight
-Comply with relevant safety operation instructions and regulations when using or disposing
Last Update：2024-04-09 19:05:48
